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Trends Cancer 2019;5:55868

Moreover, a relatively small sample size of the subgroup of patients with severe vasculogenic ED might have prevented to capture slightly significant improvements in PSV at dynamic PDU upon l-ARG supplementation, particularly in patients with borderline scores indicating severity, therefore making it challenging to provide conclusive information concerning the potential effect of l-ARG supplementation in patients with borderline severe vasculogenic ED

injection of CpG-A or CpG-B as described previously 68

It is worthy to note that cardiovascular disease and kidney disease are closely interrelated [80] and diminished renal function is strongly associated with morbidity and mortality in heart failure patients [81]

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