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For AD, we specifically used two recently published GWAS data, one from the International Genomics of Alzheimers Project (IGAP) (21,982 cases and 41,944 controls), and the other from a large meta-analysis (71,880 cases and 383,378 controls) as validation data

V.et al (2015)

As there was not significant toxicity of silymarin reported in human studies, this substance can be used with anti-tuberculosis drugs as a supplement added to the diet (13)

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Furthermore, the combined application of MNPs and PEI resulted in a more pronounced decrease in the viability and IC 50 values of A2780 cells than A2780/CP cells after 48 h