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In another study published by this group, PROTAC AK-2292 demonstrated potent cytotoxic activity against a panel of chronic myeloid leukemia (CML) cells, with IC 50 values around 0.2 to 2.2 M, as well as potent antitumor activity in xenograft tumor tissues of human CML NCO2 and KU812 cell lines in mice
[DOI] [PubMed] [Google Scholar] 26.Aher, V
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