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When administered intra-peritoneally in rats, morphine-6-sulfate exhibits much greater analgesic effect than morphine [134], suggesting that it may possess pharmacological activity similar to M6G

Additionally, genetic testing and antioxidant application might help identify GSSD and improve the prognosis

Future research could focus on optimizing the treatment plan and achieving more precise and personalized treatment with multiple targets in multiple aspects

Rather, a recent study [103] in cyclists undergoing strenuous physical training observed improved physiological adaptation with a week of oral NAC while several other studies [72, 104] have found increased signaling cytokines such as TNF- with NAC supplementation compared to a placebo, despite improved performance

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