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Research also suggests that caffeine can amplify the effects of medication for headaches and migraine attacks (16, Yet, another hypothesis believes that caffeine may act as a headache trigger for some, along with other beverages and foods, such as chocolate, alcohol, and citrus fruits like lemons ( Therefore, drinking coffee with lemon may relieve or worsen a headache, depending on the person

Nirmala, K

Additionally, TRF administration led to a reduction in the number of CD4+ senescent T cells in the dermis and spleen, consistent with the reduced expression of senescence-associated genes in splenic CD4+ T cells

Perdew, J

In animal experiments, it was discovered that ovarian cancer cells express and release extracellular vesicles (EVs) containing ARG-1, which are taken up by DCs and prevent the proliferation of T cells (101)