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doi:10.1021/acs.jmedchem.3c00908

Structural Basis of the Mercury(II)-Mediated Conformational Switching of the Dual-Function Transcriptional Regulator MerR
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By attenuating NNMT activity, 5Amino1MQ has been observed in preclinical settings to elevate NAD+ availability, enhance metabolic flux, and upregulate downstream signaling programs associated with cellular stress responses and energy expenditure (e.g., SIRT1)

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Vegetarians may obtain B12 from dairy products and eggs, but vegans, who exclude all animal products, are particularly at risk
