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Addressing the prevention of B12 deficiency and its public health implications requires a comprehensive, life-course approach based on integrated strategies targeting early detection, dietary optimisation, and effective supplementation, in order to mitigate the long-term consequences of inadequate cobalamin status (Organization, 2000)

The protective effect of this probiotic could be attributed to its ability to inhibit the migration of endotoxins into the blood and liver and further improvement in intestinal barrier function ( L

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Adenovirus particles used in the article were provided by GeneChem Company (Shanghai, China)