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, Fabersani E., Marquez A., and GauffinCano P

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doi: 10.1016/j.biopha.2017.08.132 48

By using mice deficient in glutamate-cysteine ligase (GCL) in keratinocytes, the authors found that GSH deficiency results in more DNA damage and cell death, suggesting a crucial role for the antioxidant capacity in skin integrity maintenance [93]
