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However, since human patients with mutations of FECH, which catalyzes the last step in heme synthesis, do not usually show mitochondrial iron overload, we hypothesize that the ABCB7 substrate could be a product of an earlier step in heme synthesis

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Meanwhile, heat stress reduces GSH synthesis, inhibiting the antioxidant response of tumor cells, and further exacerbating the damage caused by ROS
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2009;296:L442452

Microcirculatory alteration in low-grade gastric mucosa-associated lymphoma by Helicobacter heilmannii infection: Its relation to vascular endothelial growth factor and cyclooxygenase-2
