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Immunol Invest 51(3):602618 Kim Y, Chongviriyaphan N, Liu C, Russell RM, Wang X-D (2012) Combined -tocopherol and ascorbic acid protects against smoke-induced lung squamous metaplasia in ferrets
[DOI] [PubMed] [Google Scholar] 99.Jowsey I.R., Jiang Q., Itoh K., Yamamoto M., Hayes J.D

The accumulation of active species such as ROS will cause lipid peroxidation, and the accumulation of its products and reactive degradation products will result in ferroptosis

It seems that metabolic stress during obesity and metabolic syndrome induces a compensatory response, being characterized by increased Zn-mediated mechanisms of antioxidant protection

& Moley, K

doi:10.1038/ng0894-551a