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Molecular Pharmacology of Synthetic Cannabinoids: Delineating CB1 Receptor-Mediated Cell Signaling

It typically begins with declining blood levels (stage I), followed by low cellular levels (stage II), increased homocysteine levels and reduced DNA synthesis (stage III), and finally macrocytic anemia (stage IV)

10.1080/10715762.2018.1468564 Free Radic Res

[DOI] [PMC free article] [PubMed] [Google Scholar] 165.Dukay B., Csoboz B., Tth M.E

Juul A, Dalgaard P, Blum WF, Bang P, Hall K, Michaelsen KF, Mller J, Skakkebaek NE

The metabolic change to lactic acid fermentation is baffling at first, because it leads to a smaller net ATP production than pyruvate oxidation and therefore seems like a reduction of the cells energy production