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This creates a vicious cycle linking iron overload directly to the demyelination and neuroinflammation that characterize MS pathology

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After collecting inguinal subcutaneous adipose tissue from the mice, the tissue was incubated with collagenase D (Roche, 11088858001) at a concentration of 1.5 U/ml (with 10 mM CaCl 2 ) at 37 C for 45 min

For the purposes of this exercise, lets suppose that youre starting with 100 mg of GST-fusion protein from one liter of fermented culture

Standard oral supplements provide only 0.7% bioavailability but cost significantly less than IV therapy

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