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The dietician helps patients optimize these variables, which can reduce the severity of side effects and improve overall treatment outcomes

Negative binomial regression models followed by post hoc comparisons of estimated marginal means using the emmeans 68 package in R with Tukey adjustment for multiple comparisons were used to evaluate significant differences in CR between stage 1, stage 2 and stage 3 in each of the following: CD incidence, UC incidence, CD prevalence and UC prevalence

We also analyzed the expression of IL-6 and -8 , which however were not detectable due to the low expression level

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Disclosures Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work

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