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Even though some enzymes have been identified as possible therapeutic targets, the intricate interactions between various pathways necessitate a more organized, multitarget, process-directed therapeutic approach that seeks to concurrently interfere with several oncogenic processes in order to reduce the number of potential escape mechanisms that tumors may use (120)

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55 used a classical NKG2D CAR-T in different models of senescence to illustrate the specificity of this approach as senolytic approach

Statements estimating treatment duration and the number of treatments required are based on the typical experience of our patients, however, Individual experiences may vary