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Potential roles of mitochondrial cofactors in the adjuvant mitigation of proinflammatory acute infections, as in the case of sepsis and COVID-19 pneumonia

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Ethics declarations Ethics approval This study was conducted in accordance with the ethical guidelines of the Konkuk University Institutional Animal Care and Use Committee, which incorporate the guidelines put forth in the Declaration of Helsinki (1964)

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Mitochondria Derived from Induced Pluripotent Stem Cells (iPSCs): iPSCs exhibit high metabolic activity, with significantly higher expression of electron transport chain complexes than mature cells, enabling efficient ATP production and reducing the accumulation of ROS (9092)