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HIF- proline hydroxylation Jaakkola and colleagues [88] recently indicated that the interaction between human pVHL and a specific domain of the HIF-1 subunit is regulated through hydroxylation of a proline residue (HIF-1 Pro564) by an enzyme termed by the authors HIF- prolyl-hydroxylase (HIF-PH)

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A recent meta-analysis revealed that the cerebrospinal fluid HCY levels among ALS patients were significantly higher than those in controls, while no significant differences were observed in the plasma levels of HCY, folic acid, or vitamin B12 between ALS patients and controls [319]

2022;162:112904 [Google Scholar] Ginseng root extract attenuates inflammation by inhibiting the MAPK/NF-B signaling pathway and activating autophagy and p62-Nrf2-Keap1 signaling in vitro and in vivo
