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For in vivo validation, we established a photoaging mouse model to investigate the protective effects of DBP and different DBP formulations

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Their pups were divided into six groups of eight (three male and three female): a control group receiving normal saline, a social isolation stress group (SIS + NS) also receiving saline, and a social isolation stress group treated with intraperitoneal NAC (SIS + NAC)

1 2 3 4 Expert Opinion on Pharmacotherapy

FIGURE 3 However, the limitation of passive targeting is that its targeting is relatively weak, and it is greatly affected by tumor heterogeneity and individual differences ( 2.2.2 Active targeting Active targeting, by contrast, modifies specific targeting molecules (such as antibodies, peptides, aptamers, etc.) on the surface of the nanocarriers so that they can accurately recognize and bind to specific antigens or receptors on the surface of tumor cells, thus achieving efficient drug delivery