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The efficacy of topical antioxidants such as vitamin C, vitamin E, ferulic acid, niacinamide and copper peptides is supported by extensive in-vitro, in-vivo and clinical research. Masaki H

A recent study has shown that skin samples with higher demodex densities exhibited enhanced expression of genes for interleukin (IL)-8, IL-1, tumor necrosis factor (TNF)-, cyclooxygenase-1, and the inflammasome [52]
Their ability to regulate macrophage polarization, suppress pro-inflammatory cytokines, and restore epithelial integrity highlights their promise as therapeutic agents for IBD and other inflammatory gut disorders [54,55,56,57]

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doi: 10.1093/cdn/nzaa045_038
Endothelial damage Endothelial cells are important regulators of the immune system (308)
