ghk cu peptide for acne scars Copper Serum GHK-Cu Peptide Before and After

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33 1990 Discovery of a Peptide-based Renin Inhibitor with Oral Bioavailability and Efficacy Kleinert HD, Rosenberg SH, Baker WR, Stein HH, Klinghofer V, Barlow J, Spina K, Polakowski J, Kovar P, Cohen J and Denissen J Science 257 1992 In Search of Ideal Antihypertensive Drugs: Progress in Five Decades Lien EJ, Gao H and Lien LL Prog Drug Res

Although the drug was administered topically, systemic suppression of VEGF occurred, suggesting potential off-target effects beyond the ocular compartment (Sultana and Scondotto 2020)