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doi: 10.1002/pmic.201800419

Less commonly, TRT may be associated with more serious risks , including elevated red blood cell counts (hematocrit), changes in cholesterol levels, blood clots, or prostate-related concerns, particularly in men with underlying risk factors

Speak With a Physician 100% Naturally occurring mitochondrial peptide bioidentical to human MOTS-c 10+ Years of research validating safety and metabolic benefits MOTS-c is a mitochondrial-derived peptide that regulates cellular energy metabolism by activating AMPK, a master metabolic switch
Andersson A, Brattstrm L, Israelsson B, Isaksson A, Hamfelt A, and Hultberg B (1992)

The solution looks identical whether the peptide is intact or degraded

Since regulation of KCC2 expression is also mediated by BDNF (Rivera et al