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doi: 10.1007/s00702-014-1180-8

with lesser fat storage being the primary reason for such

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Secondary l-carnitine deficiency in the body generally occurs due to malabsorption, defective biosynthesis, increased use or degradation, and defective kidney re-uptake

Transdermal estradiol, delivered via patch or cream rather than oral tablet, bypasses first-pass hepatic metabolism
