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In contact dermatitis and atopic dermatitis, inhibition of 15-LOX inhibits podosome formation in dendritic cells, downregulates the antigen uptake and cell migration capabilities, and contributes to the alleviation of skin inflammation (Han et al., 2017)

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In mammals, serine degradation is predominantly catalyzed by serine hydroxymethyltransferase (SHMT), which transfers the -carbon of serine to tetrahydrofolate (THF), generating glycine and 5,10-methylenetetrahydrofolate (5,10-CH 2 -THF)

Alcohol elevates blood pressure by influencing sodium and water reabsorption and activating the sympathetic nervous system

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