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Among the cysteine residues in human Keap1, Cys 151, 273 and 288 are highly reactive and play an essential role for repression of Nrf2/ARE activation (Saito et al., 2016)

10.1016/j.phymed.2020.153270 339 ZhaoX

Gao RF, Li X, Xiang HY, Yang H, Lv CY, Sun XL, Chen HZ, Gao Y, Yang JS, Luo W, Yang YQ, Tang YH
Furthermore, the ArsC tag not only enhanced the solubility but also boosted the overall expression level of eGFP (Fig
Cancer 116 , 57165724 (2010)

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