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Molecular Pharmacology of Synthetic Cannabinoids: Delineating CB1 Receptor-Mediated Cell Signaling

Vella A, Bouatia-Naji N, Heude B, Cooper JD, Lowe CE, Petry C, Ring SM, Dunger DB, Todd JA, Ong KK

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Following intranasal administration, ADSC-Exos rapidly accumulated in brain tissue, exerting significant neuroprotective effectsincluding reduced neuronal apoptosis and enhanced autophagymediated through AMPK-mTOR pathway activation, ultimately mitigating neuroinflammation

The main causes of NIHL include mechanical damage from noise itself and toxic damage from oxidative stress

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