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It also reduced TNF-alpha levels, a key inflammatory cytokine

Combined CAR T-cell therapy is emerging as an important approach for treating autoimmune diseases

doi: 10.1017/S0031182000066269

Another compound that was identified as potent BACH1-inhibitor was the phytocannabinoid cannabidiol (CBD), which induces nuclear export and degradation of the transcription factor ( In vitro models have confirmed CBDs antioxidant and anti-inflammatory properties, acting through HMOX-1 and inducing the downregulation of pro-inflammatory cytokines (Juknat et al., 2016

Nonetheless, the changes in the metabolic landscape at a cellular level in such neurodegenerative disorders remain poorly characterized

Sometimes seeing these steps in action can make all the difference in making them a permanent habit