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The Th cell subgroups mainly consist of Th1, Th2, and Th17 cells, which play an active role in both cellular and humoral immunity by secreting unique cytokines specific to their distinct functions [86]
The European Federation of Neurological Societies guidelines on neuropathy recommend pregabalin, gabapentin, duloxetine, tricyclic antidepressants, and venlafaxine for first-line treatment, with opioids and tramadol reserved for second-line therapy [37]
Its considered one of the most important antioxidants in the human body (5)
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