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continue vitamin supplementation during treatment and for 21 days after the last dose of pemetrexed to reduce the severity of hematologic and gastrointestinal toxicity of pemetrexed [see Dosage and Administration (2.4)]

These products are accessible without a prescription, making them available over the counter

Reference values are not different for older adults because unlike MMA, serum B12 does not change substantially with age in healthy, well-nourished individuals (Figure 4)

Since then, it has been the subject of extensive research

While medication one day past the BUD may still be effective, you have no way to verify this without laboratory testing

B12 injections can help repair and protect nerve function, reducing the risk of neurological problems