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Under some pathophysiological circumstances, endothelium-derived vasoconstricting factors, such as ET-1, AT-II, urotensin II, superoxide anions, vasoconstrictor prostaglandins and thromboxane A 2 , can be released and contribute to the paradoxical vasoconstrictor effects

Ntnen R, Gaillard AWK, Mantysalo S (1978)

larger multicenter prospective studies are needed to confirm these observations and to inform optimal monitoring and management strategies

Bioorg Med Chem Lett 21:42594262 [DOI] [PubMed] [Google Scholar] Pacher P, Beckman JS, Liaudet L (2007) Nitric oxide and peroxynitrite in health and disease

By integrating metabolic regulation with inflammation suppression, SIRT1 represents a promising therapeutic target in MASLD and related inflammatory liver diseases

(B) Following 2 h of-exposure to Sch A or Sch B, the mRNA level of thioredoxin (TRX) was measured, as described in Fig 6