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This increase may also reflect a heightened risk for additional complications, such as bleeding and coagulation disorders, associated with hepatic inflammation [206]

found that blocking activin receptor-like kinase 4/5 (ALK4/5, one of the TGF- receptors) could activate Nrf2 signaling to inhibit erastin-induced ferroptosis in HK-2 cells[131]

Future directions Further investigation of molecular mechanisms linking the processes of angiogenesis and neurodegeneration is essential

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doi: 10.1016/j.heliyon.2021.e07615 197

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