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In a 12-week clinical study, obese participants taking 1 mg of AOD-9604 daily lost about 2.62.8 kg (56 lbs) on average more than triple the weight loss of the placebo group
Methotrexate belongs to a class of drugs known as antimetabolites

doi:10.1016/j.ejphar.2018.08.014 Bonechi C, Lamponi S, Donati A, et al
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