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It upregulates growth factors including VEGF and EGF

The same review notes one comparison in which fatigue was 2% on placebo versus 6% on 20 mg daily , which supports a medication effect rather than coincidence

This means you don't have to worry as much about the "perfect" timing

A 29 or 30 gauge needle minimizes discomfort during injection

The neuroprotective effect of DMSO observed in this study agrees with other studies reported by (Torre et al., 1973) who first reported the potential therapeutic effect of DMSO in central nervous system injury

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