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Independently, GHK-Cu modulates the transcription of genes governing extracellular matrix synthesis, antioxidant defense (SOD, glutathione peroxidase, ferritin), and inflammatory signaling pathways including NF-B and TGF-1 (Pickart & Margolina, 2018)

MLKL in adipocytes drives obesity-induced metabolic dysfunction and insulin resistance To evaluate the role of MLKL in obesity-induced metabolic dysfunction, we assessed glucose homeostasis and insulin sensitivity in Mlkl Adi-KO and WT mice after 16 weeks of feeding with either NCD or HFD

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2018;9(9):CD001127