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10.1016/s0928-4257(99)00119-9 [DOI] [PubMed] [Google Scholar] Sikiric P., Mikus D., Seiwerth S., Grabarevic Z., Rucman R., Petek M., et al

These modifications reduce binding to IGF-binding proteins and enhance stability during laboratory studies

There is also evidence of substantial diversity at the transcriptome level between endothelial cells from different brain regions (Schaeffer and Iadecola, 2021)

Most of the existing literature addresses adults, focuses narrowly on the mechanism, or ignores the developmental pharmacology that makes pediatric patients different (Lanvers-Kaminsky and Ciarimboli, 2017