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Freeze-thaw: Avoid repeated freeze-thaw cycles of the reconstituted solution

doi: 10.1080/19490976.2023.2265578 218 IwanagaTTakahashi-IwanagaH

Cost effectiveness of tibial nonunion treatment: a comparison between rhBMP-7 and autologous bone graft in two Italian centres

Regulatory bodies like the FDA and EMA necessitate thorough physicochemical characterisation, stability information, and proof of therapeutic equivalency, which can be challenging for these heterogeneous systems [124]

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Inject a small volume of air into the vial first to prevent vacuum