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X.Y., Z.X.R., and M.T.G

Side Effect 3: Allergic Reactions Though rare, allergic reactions require immediate medical attention

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Activation of Akt/Wnt/-catenin signal transduction by CXXL12/CXCR4 induces the expression of VE-cadherin and stabilizes its interaction with VE-cadherin-associated phosphatases to maintain the integrity of endothelial cells and favours a contractile phenotype over a synthetic phenotype in arterial SMCs, thus inhibiting atherosclerosis

It also means allergic reactions are unlikely, though not impossible, since any foreign substance can theoretically trigger sensitivity in susceptible individuals