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When stratified by administration route, the average percentage reductions were: Intramuscular (IM): 48.3% Sublingual: 30.7% Oral: 30.3% These results suggest that IM administration leads the most pronounced homocysteine reduction, however, sublingual and oral routes also demonstrate clinically relevant effects

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In a study of 68 paired samples, the average expression level was significantly higher in R/R patients compared to NDMM patients, highlighting the potential of CD38 as a target for imaging and therapy [97]

doi: 10.1371/journal.pone.0250165