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Q: When is Mecobalamin Injection recommended

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Nicotinamide N-methyltransferase (NNMT), is a naturally occurring enzyme involved in fat accumulation and energy metabolism, is inhibited by it (1)

However, since as early as 1968, oral vitamin B 12 has been shown to have an efficacy equal to that of injections in the treatment of pernicious anemia and other B 12 deficiency states

This vascular healing can help stabilize the erratic autonomic nervous system signaling that drives the rapid heart rate and dizziness associated with POTS

The timeline for tendinopathy improvement tends to follow a pattern where initial pain reduction occurs within the first week, with progressive functional improvement over 4 to 6 weeks