gpx4 glutathione peroxidase 4: a new player in neurodegeneration? Orthogonal Strategies Rat Glutathione Peroxidase 4 (GPX4)

Based on the here-presented biochemical, structural and computational evidence, we propose that arGSTs utilize a GSH-dependent Brnsted base mechanism for conversion of the semi-stable LDOX product flavan-3,3,4-triol ( 4 ) or flavan-3-on-4-ol ( 7 ) into flav-2-en-3,4-diol ( 8 -B4), the 4-hydration species of cyanidin ( 8 ) (Extended Data Fig

Description Journal Title STAR Protoc Conference Name Journal ISSN 2666-1667 2666-1667 2666-1667 Volume Title Publisher Elsevier Publisher DOI Rights and licensing Except where otherwised noted, this item's license is described as Attribution 4.0 International Sponsorship Cambridge University Hospitals NHS Foundation Trust (CUH) (146281) This research was supported by the NIHR Cambridge Biomedical Research Centre (NIHR203312).

As of November 2024, the PDS version stands at 0.4

2 , S49S67 (2019)

Low red blood cell vitamin C concentrations induce red blood cell fragility: A link to diabetes via glucose, glucose transporters, and dehydroascorbic acid

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