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Many studies have shown that exosomes play a crucial role in neurogenesis and are even of potential significance in treating some neurological diseases (72)

D., and Braak H., Parkinson's Disease: A Dualhit Hypothesis, Neuropathology & Applied Neurobiology 33, no

[7] Centers for Disease Control and Prevention
MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction

Immunometabolism governs dendritic cell and macrophage function

What the broader literature describes is remodeling, not a one-way pile-up
