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Nature 586 , 578582 (2020)
NAD+ therapy represents the cutting-edge of iv bar treatments
Another fundamental characteristic of ergothioneine is that it has a very long half-life around 30 days compared with the half-life of classic antioxidants of between 30 seconds and 30 minutes
doi: 10.1038/nrc1014 2 ParkJREggertACaronH
MK-677 (half-life 24 hours) requires a longer taper 3-4 weeks minimum because its prolonged receptor occupancy causes deeper suppression that takes 28-35 days to fully resolve
