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Trial data show that ongoing administration is required to maintain weight loss, as discontinuation leads to weight regain (Rubino et al., 2021

Q15: What do studies show

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If you can pinch at least 2 inches of skin at your injection site, a 6 mm needle at 90 degrees will reliably deposit the medication in the subcutaneous layer

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The relevance of these observations is currently being validated in in vivo models (105)