increased glutathione peroxidase activity in an individual with keshan disease - overview GPX1 (Glutathione Peroxidase, GSHPx) Gene

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Pernicious Anaemia & Other Macrocytic Anaemias

Watanabe S, Moniaga CS, Nielsen S, Hara-Chikuma M

Calissendorff, J., Mikulski, E., Larsen, E

Conjugation reactions usually involve metabolite activation by a highenergy intermediate and have been classified into two general types: type I (e.g., glucuronidation and sulfonation), in which an activated conjugating agent combines with substrate to yield the conjugated product, and type II (e.g., amino acid conjugation), in which the substrate is activated and then combined with an amino acid to yield a conjugated product (Hodgson, 2004)

Important caveat: Side effect data comes primarily from animal studies