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In a pharmacokinetic study where five normal adult male volunteers received an oral dose of [ 3H-methyl]-L-carnitine following 15 days of a high carnitine diet and additional carnitine supplement, 58 to 65% of the administered radioactive dose was recovered in the urine and feces in 5 to 11 days

So as you drink, and you lose water, the tissues around your brain start to shrink

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Variations in its catalytic activity of P-450 3A4 are important in issues of bioavailability and drug-drug interactions [44]
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