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Despite its limited clinical application, the mechanism of H 2 S release has been demonstrated in several studies

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Brune M, Rossander L, Hallberg L

Although reperfusion, whether spontaneous or achieved through percutaneous coronary intervention, restores blood flow, it simultaneously provokes ischemiareperfusion injury (IRI) through a sudden burst of ROS, exacerbating myocardial damage

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Advances in structural biology and predictive modelling of flavoprotein-cofactor interactions promise to refine genetic diagnostics and pave the way for genotype-guided, riboflavin-based precision therapies