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While this inflammatory cascade is essential for microbial clearance, excessive or prolonged activation results in collateral tissue damage and immunosuppression (Giamarellos-Bourboulis et al., 2024

VB12 could regulate oxidative stress-related proteins and improve mitochondrial autophagy by increasing the expression of SIRT1

In one study, Lee, Cell Metabolism demonstrated that MOTS-c improved insulin resistance and protected against diet-induced obesity in mice

Am J Obstet Gynecol (2013) 208(3):226.e1.e7

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doi: 10.1016/j.ceca.2019.06.004 346
