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Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes

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Domain organization of phytochelatin synthase

G., Arul, V., Kumar, M

It allows the glutathione to pass through the digestive system unharmed and reach the small intestine, where it can be absorbed directly into the bloodstream

As a consequence, human cells with additional chromosomes suffer from proteotoxic stress, as documented by increased sensitivity to chaperone inhibitors, accumulation of ubiquitin- and p62-positive cytosolic bodies and increased lysosomal stress 8,9,14,15,16,18