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Wasn't super severe

Treatment of cultured macrophages with cholesterol crystals leads to rapid phagocytosis of the crystals, which are then stored in lipid droplets (LDs)

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The loss of the amino-terminal region of Group VIA-2 phospholipase A 2 resulted in a more active enzyme which accelerated membrane phospholipid destruction

Xiong et al
Biomacromol 15(9):34493462