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Dietary interventions, such as increasing fiber, polyphenols, and probiotics, can modulate the gut microbiota to reduce TMAO production

Nutritional interventions in the management of fibromyalgia syndrome

By providing an exogenous source of fumarate, this specific supplement formulation acts as a direct catalyst for the Krebs cycle

This doesnt have to be complicated or time-consuming

This is changing as the medical community increasingly recognizes fibromyalgia as a pain disorder rooted in altered pain processing, with supportive evidence from neuroimaging, quantitative sensory testing, and, in some patients, small-fiber pathology (damage or dysfunction involving small nerve fibers)

doi: 10.1016/0003-9861(54)90064-8