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Prxs receive new oxygen at the mercaptan active site to protect proteins from oxidation by hydrogen peroxide (Rhee et al., 2012)

IGF-1 LR3 is a modified version of natural IGF-1 with two engineered changes: a 13-amino-acid N-terminal extension and an arginine substitution at position 3

The previous findings of our lab (32) and others (33) have demonstrated that brain GSH concentration in older adults is significantly lower than in younger adults by over 10%

Data acquisition was using an Agilent 6546 Q-TOF instrument (ESI) with optimized parameters: gas temp 300 C, drying/sheath gas 8/11 L/min, capillary voltage 3500 V, and spray voltages 500/1000 V

Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock

These findings demonstrate that there are several therapeutic approaches targeting oxidative stress in FECD