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Intravenous methylcobalamin treatment for uremic and diabetic neuropathy in chronic hemodialysis patients

Phase I metabolism alters the chemical structure of the drug by functionalization reactions which introduce a polar functional group onto the molecule

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168 Recent studies also show that knocking down PPAR coactivator 1 (PGC1), an important transcriptional coactivator regulating CPT1A and CPT1B, obviously decreases the ratio of NADPH/NADP + and ATP levels, impairing radiation resistance in nasopharyngeal carcinoma (NPC) cells
10.1016/j.molliq.2025.127865 48 Di MariG
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